Clinical Care Guidance
The signs and symptoms of COVID-19 present at illness onset vary, but over the course of the disease many people with COVID-19 will experience the following:
- Fever or chills
- Shortness of breath or difficulty breathing
- Muscle or body aches
- New loss of taste or smell
- Sore throat
- Congestion or runny nose
- Nausea or vomiting
The National Institutes of Health (NIH) provides treatment and management recommendations for COVID-19 patients. Their treatment guidelines are updated regularly based on new data.
For more information on clinical care and managing COVID-19 patients, visit the CDC website.
Ending Home Isolation
Persons with COVID-19 who have symptoms and were directed to care for themselves at home may discontinue isolation under the following conditions:
- At least 10 days have passed since symptom onset and
- At least 24 hours have passed since the resolution of fever without the use of fever-reducing medications and
- Other symptoms have improved.
Persons infected with SARS-CoV-2 who never develop COVID-19 symptoms may discontinue isolation and other precautions 10 days after the date of their first positive RT-PCR test for SARS-CoV-2 RNA
For hospitalized patients, see Discontinuation of Transmission-Based Precautions and Disposition of Patients with COVID-19 in Healthcare Settings (Interim Guidance).
For more information on ending home isolation for people with COVID-19, visit the CDC website.
- Additional Resources